Usage NET-QUBIC data, release 3


To support scientific research, the Steering Committee of the NET-QUBIC Consortium decided to facilitate early data releases. In this third data release, data and samples of all 739 included patients and 262 caregivers collected up to 6 months follow-up are available.

The NET-QUBIC Data Warehouse and Biobank consists of longitudinal data of newly-diagnosed head and neck cancer patients and their informal caregivers. The primary objective of the NET-QUBIC-project is to describe the long term course of quality of life in newly-diagnosed head and neck cancer patients and their informal caregivers and to identify cancer-related, personal, biological, psycho-behavioural, physical, lifestyle-related, and social determinants of quality of life. The intent of the NET-QUBIC Date Warehouse and Biobank is to support all kinds of scientific research in head and neck cancer patients and their informal caregivers.


Research proposals

Available data and samples in the third data release

Baseline data and samples of all 739 patients, as well as 3-months follow-up data (n=541) and 6 months (n=585) follow-up data and samples are available. Table 1 provides information on sex, age, tumor location, TNM stage, and treatment modality of these included patients. In addition, Table 2 provides information on the (number of) available samples and measurements per time point.

Also, data and samples on baseline of all 262 caregivers, as well as 3-months (n=193) and 6 months (n=170) follow-up data are available. Table 3 provides information on sex and age of the caregivers, and their patient’s tumor location, TNM stage, and treatment modality. In addition, Table 4 provides information on the exact (number of) available samples and measurements per time point.

Data and biomaterials not yet available in the third data release

The following data will not yet be released in this third data release, namely voice recordings, data on healthcare utilization,  and data needed for the already approved NET-QUBIC (PhD) projects.

These projects include:

  1. The course of health related quality of life in relation to survival (Amsterdam UMC, location VUmc, project leader IM Verdonck-de Leeuw)
  2. Depression in head and neck cancer patients and the relation with survival (Amsterdam UMC, location VUmc, project leader IM Verdonck-de Leeuw),
  3. Treatment optimization in elderly head and neck cancer patients (UMCG, project leader JA Langendijk),
  4. Development and validation of predictive models for objectively and subjectively measured salivary, mastication, and swallowing function in relation to quality of life among patients treated for head and neck cancer (UMCU, project leader CHJ Terhaard),
  5. Fear of recurrence in head and neck cancer patients (Radboud UMC, project leaders RP Takes and JB Prins).
  6. Sleep disturbances in newly diagnosed head and neck cancer patients (Vrije Universiteit Amsterdam, project leader IM Verdonck-de Leeuw).

Procedure 
More information about the procedure can be found here.

Study procedures NET-QUBIC

For more information about Annex I, IV, V, VI and VII, click here

Time schedule

Between October 1, 2019 and January 1, 2020, applicants can submit their research proposal.

In February 2020 the NET-QUBIC steering committee will decide on the research proposal, and the applicant will be informed on the decision.

Questions?

For questions, please contact:
Prof Irma Verdonck-de Leeuw
data.netqubic@vumc.nl

Kubus

Project Kubus
VUmc, Afdeling KNO
Postbus 7057
1007 MB Amsterdam
info.netqubic@vumc.nl