Table 2. Overview available samples and measurements
 

 Biobank

 

 Subject

 

 

Biobank

Oral rinse

 

Blood

 

Saliva

 

Tumour tissue

 Patient-reported outcome measures

 

 Subject

 Instrument

 

Measured once:

 

NQ_x101

Demographics

Age and gender

NQ_x103

Education and literacy

Education and literacy

NQ_x104

Country of birth and family

Country of birth and family

NQ_x112

Personality (big five)

NEO Five Factor Inventory (NEO-FFI)

NQ_x113

Locus of control

Pearlin Schooler and Mastery Scale (PSMS)

NQ_x115

Coping

Utrecht Coping List (UCL)

NQ_x116

Social Desirability

Social desirability questionnaire (study-specific questionnaire)

NQ_x127

Fertility

Study-specific questionnaire (women only)

 

 

 

 

Measured every time point:

 

 

Questionnaire A

 

NQ_x102

Weight

Gender, age, self-reported weight

NQ_x106

Smoking and nicotine dependence

Smoking habits (study-specific questionnaire)

NQ_x107

Alcohol intake and dependence

Alcohol (study-specific questionnaire)

NQ_x108

Drugs use

Drugs (study-specific questionnaire)

NQ_x109

Generic quality of life

EuroQol (EQ-5D + VAS)

NQ_x110

Disease-specific quality of life

EORTC QLQ-C30

NQ_x111

Tumour-specific quality of life

EORTC QLQ-H&N35

NQ_x114

Coping

Mental Adjustment to Cancer (MAC)

NQ_x117

Severity anxiety/depression

Hospital Anxiety and Depression Scale (HADS)

NQ_x118

Fatigue

Multidimensional Fatigue Inventory (MFI)

NQ_x119

Swallowing

Swallowing Quality of Life Questionnaire (SwalQoL)

NQ_x120

Speech

Speech Handicap Index (SHI)

NQ_x121

Xerostomia

Groningen Radiation Induced Xerostomia (GRIX)

NQ_x122

Shoulder problems

Shoulder Disability Questionnaire (SDQ)

NQ_x123

Fear of recurrence

Cancer Worry Scale (CWS)

NQ_x128

Social support

Social Support List – Interactions (SSL-I12)

NQ_x130

Physical activity

Physical Activity Scale for the Elderly (PASE)

 

 

 

 

Questionnaire B

 

NQ_x202

Participation

Impact on Participation and Autonomy (IPA)

NQ_x203

Self-perceived neurocognitive function

Cognitive Failures Questionnaire (CFQ)

NQ_x204

Self-efficacy

Generalized Self-Efficacy Scale (GSE)

NQ_x205

Sleep quality

Pittsburgh Sleep Quality Index (PSQI)

NQ_x206

Life events

Brugha/List of Threatening Experiences

NQ_x207

Post-traumatic stress

Impact of Event Scale-Revised (IES-R)

NQ_x208

Loneliness

Loneliness Scale (deJong Gierveld)

NQ_x209

Hearing

Caron

NQ_x210

Sexual functioning – men

International Index of Erectile Function (IIEF)

NQ_x211

Sexual functioning – women

 Female Sexual Function Index (FSFI)

NQ_x212

Supportive care needs

Supportive Care Needs Survey Short-Form 34 (SCNS-SF34) and  SCNS head and neck cancer module (SCNS-HNC)

NQ_x214

Leisure activities

 Study-specific questionnaire

 Home based interview and test

 

Subject

 Instrument

 

Measured during home-based visit:

 

NQ_x302

 Anxiety disorders

WHO--Composite International Diagnostic Interview (CIDI)

NQ_x303

 Major Depressive Disorder (MDD)

 WHO--Composite International Diagnostic Interview (CIDI) 

NQ_x304

Verbal learning and verbal recall: immediate recall

 Hopkins Verbal Learning Test (HVLT)

NQ_x305

Visual motor scanning speed

 Trailmaking A

NQ_x306

Executive functioning

 Trailmaking B

NQ_x307

Verbal fluency

 Controlled Oral Word Association Test (COWA)

NQ_x308

Daily life

 Instrumental Activities Daily Life (IADL)

NQ_x309

Pain

 Brief Pain Inventory (BPI)

  NQ_x310

Verbal learning and verbal recall: Delayed

 Hopkins Verbal Learning Test (HVLT) - Delayed Recall

NQ_x311

Blood pressure

 Systolic and diastolic blood pressure

NQ_x312

Body composition

 Weight, height, BMI, circumferences (waist and hip), skinfolds (4 measurements)

NQ_x313

Pulmonary function

 Peak flow

NQ_x314

Muscle strength

 JAMAR handgrip dynamometer, 30s chair stand test

NQ_x315

Nutrition status

 Mini Nutritional Assessment (MNA)

NQ_x317

Oral and shoulder function

 Functional Rehabilitation Outcome Grades (FROG)

NQ_x318

Cardiorespiratory fitness

 Chester Step test

NQ_001

Dietary intake

 Recall dietary intake

NQ_003

Heart rate

 Polar

 

 

 

 

Measured after home-based visit:

 

NQ_002

Objectively measured physical activity

 Accelerometer (gt3x en agd)

 Clinical data

NQ_x401

Baseline eCRF

 

NQ_x402

Follow-up eCRF (2 years follow-up)

 

 

Kubus

Project Kubus
VUmc, Afdeling KNO
Postbus 7057
1007 MB Amsterdam
info.netqubic@vumc.nl