Table 2. Overview available samples and measurements per outcome per time point (n=739). Click here for a pdf.


Biobank
 

 

Subject

 

T0

M3

M6

 NQ_x002

 Biobank

Oral rinse

662

NA

550

 

 

Blood

657

NA

523

 

 

Saliva

423

NA

409

 

 

Tumour tissue

155

NA

NA

 


Patient reported outcome measures
 

 

Subject

Instrument

T0

M3

M6

 

 Measured once:

 

 

 

 

 NQ_x101

 Demographics

 Age and gender

739

NA

NA

 NQ_x103

 Education and literacy

 Education and literacy

644

NA

NA

 NQ_x104

 Country of birth and family

 Country of birth and family

636

NA

NA

 NQ_x112

 Personality (big five)

 NEO Five Factor Inventory (NEO-FFI)

574

NA

NA

 NQ_x113

 Locus of control

 Pearlin Schooler and Mastery Scale (PSMS)

571

NA

NA

 NQ_x115

 Coping

 Utrecht Coping List (UCL)

573

NA

NA

 NQ_x116

 Social Desirability

 Social desirability questionnaire (study-   specific questionnaire)

571

NA

NA

 NQ_x127

 Fertility

 Study-specific questionnaire (women only)

142

NA

NA

 

 

 

 

 

 

 

 Measured every time point:

 

 

 

 

 

 Questionnaire A

 

579

541

478

NQ_x102

Weight

Gender, age, self-reported weight

 

 

 

NQ_x106

Smoking and nicotine dependence

Smoking habits (study-specific questionnaire)

 

 

 

NQ_x107

Alcohol intake and dependence

Alcohol (study-specific questionnaire)

 

 

 

NQ_x108

Drugs use

Drugs (study-specific questionnaire)

 

 

 

NQ_x109

Generic quality of life

EuroQol (EQ-5D + VAS)

 

 

 

NQ_x110

Disease-specific quality of life

EORTC QLQ-C30

 

 

 

NQ_x111

Tumour-specific quality of life

EORTC QLQ-H&N35

 

 

 

NQ_x114

Coping

Mental Adjustment to Cancer (MAC)

 

 

 

NQ_x117

Severity anxiety/depression

Hospital Anxiety and Depression Scale (HADS)1

 

 

 

NQ_x118

Fatigue

Multidimensional Fatigue Inventory (MFI)

 

 

 

NQ_x119

Swallowing

Swallowing Quality of Life Questionnaire (SwalQoL)

 

 

 

NQ_x120

Speech

Speech Handicap Index (SHI)

 

 

 

NQ_x121

Xerostomia

Groningen Radiation Induced Xerostomia (GRIX)

 

 

 

NQ_x122

Shoulder problems

Shoulder Disability Questionnaire (SDQ)

 

 

 

NQ_x123

Fear of recurrence

Cancer Worry Scale (CWS)1

 

 

 

NQ_x128

Social support

Social Support List – Interactions (SSL-I12)

 

 

 

NQ_x130

Physical activity

Physical Activity Scale for the Elderly (PASE)

 

 

 

 

 

 

 

 

 

 

Questionnaire B

 

569

503

402

NQ_x202

Participation

Impact on Participation and Autonomy (IPA)

 

 

 

NQ_x203

Self-perceived neurocognitive function

Cognitive Failures Questionnaire (CFQ)

 

 

 

NQ_x204

Self-efficacy

Generalized Self-Efficacy Scale (GSE)

 

 

 

NQ_x205

Sleep quality

Pittsburgh Sleep Quality Index (PSQI)

 

 

 

NQ_x206

Life events

Brugha/List of Threatening Experiences

 

 

 

NQ_x207

Post-traumatic stress

Impact of Event Scale-Revised (IES-R)

 

 

 

NQ_x208

Loneliness

Loneliness Scale (deJong Gierveld)

 

 

 

NQ_x209

Hearing

Caron

 

 

 

NQ_x210

Sexual functioning – men

International Index of Erectile Function (IIEF)

 

 

 

NQ_x211

Sexual functioning – women

 Female Sexual Function Index (FSFI)

 

 

 

NQ_x212

Supportive care needs

Supportive Care Needs Survey Short-Form 34 (SCNS-SF34) and  SCNS head and neck cancer module (SCNS-HNC)

 

 

 

NQ_x214

 Leisure activities

 Study-specific questionnaire

 

 

 

 

 

 

 

 

 


Home-based interview and tests
 

 

Subject

Instrument

T0

M3

M6

 

 Measured during home-based visit:

 

580

NA

539

NQ_x302

Anxiety

WHO--Composite International Diagnostic Interview (CIDI) – Anxiety disorders (generalized anxiety disorder (GAD), social phobia  (SOC), panic disorder (PAN) and agoraphobia (AG)1

 

 

 

NQ_x303

Depression

WHO--Composite International Diagnostic Interview (CIDI) – Major Depressive Disorder (MDD)1

 

 

 

NQ_x304

Verbal learning and verbal recall: immediate recall

 Hopkins Verbal Learning Test (HVLT)

 

 

 

NQ_x305

Visual motor scanning speed

Trailmaking A

 

 

 

NQ_x306

Executive functioning

Trailmaking B

 

 

 

NQ_x307

Verbal fluency

Controlled Oral Word Association Test (COWA)

 

 

 

NQ_x308

Daily life

Instrumental Activities Daily Life (IADL)

 

 

 

NQ_x309

Pain

Brief Pain Inventory (BPI)

 

 

 

NQ_x310

Verbal learning and verbal recall: Delayed

Hopkins Verbal Learning Test (HVLT) – Delayed Recall

 

 

 

NQ_x311

Blood pressure

Systolic and diastolic blood pressure

 

 

 

NQ_x312

Body composition

Weight, height, BMI, circumferences (waist andip), skinfolds (4  measurements)

 

 

 

NQ_x313

Pulmonary function

Peak flow

 

 

 

NQ_x314

Muscle strength

JAMAR handgrip dynamometer, 30s chair stand test

 

 

 

NQ_x315

Nutrition status

Mini Nutritional Assessment (MNA)

 

 

 

NQ_x317

Oral and shoulder function

Functional Rehabilitation Outcome Grades (FROG)

 

 

 

NQ_x318

Cardiorespiratory fitness

Chester Step test

 

 

 

 

 

 

 

 

 

 

Measured after home-based visit:

 

 

 

 

NQ_001

Dietary intake

 Recall dietary intake

581

NA

518

NQ_002

Objectively measured physical activity

 Accelerometer (gt3x en agd)

381

NA

422

NQ_003

Heart rate

 Polar

 

 

 

 

 

 

 

 

 


Clinical data
 

NQ_x401

Baseline eCRF

 

739

NA

NA


1 These measures are part of the already approved PhD-projects. Note: This table provides an overview of the available data in the early data release.
It should be noted that for the actual analyses the total number of participants

 

Kubus

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